副教授
邮箱:changyuan218@163.com
地址:院士楼-420
教育:
PhD(分析化学)西南大学,师从袁若教授,2013.09-2019.06
BS(化学)商丘师范学院,2009.09-2013.06
工作经历:
2019.07-2021.09 博士后,资源环境学院,西南大学
2021.09-2022.05 讲师,化学化工学院,河南师范大学
2022.06-至今 副教授(特聘),冠军白菜策略网cmp8论坛,冠军白菜策略网cmp8论坛
重要奖项和荣誉:
2014-2018 获西南大学科研论文“优秀科技成果奖”(5次)
2013-2017 获西南大学“三好研究生”(3次)
2015 获硕士研究生“国家奖学金”
2016 获西南大学“优秀毕业生”
2013-2015 获西南大学全额奖学金(3次)
研究与近期代表性论文(选):
主要以纳米材料及生物电分析为中心,开展纳米材料精细制备、DNA纳米装置设计合成、电化学传感器构建等研究工作,擅长纳米材料结构构筑、电化学分析及机理揭示、各种疾病标志物及环境污染物检测分析等。在领域期刊包括Analytical Chemistry、Advanced Science、Chemical Science、Chemical Communications、ACS Applied Materials & Interfaces、Biosensors and Bioelectronics、Journal of Materials Chemistry B等发表SCI收录论文20余篇。主持国家自然科学基金青年项目、中国博士后特别资助项目、中国博士后面上项目、重庆市自然科学基金项目各一项。
发表论文:
1)Yuanyuan Chang, Sai Xu, Yunrui Li, Wenxi Hu, Hang Li, Ruo Yuan,* and Yaqin Chai*, DNA Three-Way Junction with Multiple Recognition Regions Mediated an Unconfined DNA Walker for Electrochemical Ultrasensitive Detection of miRNA-182-5p. Anal. Chem., 2021, 93, 12981-12986.
2)Yuanyuan Chang, Xiaolu Tang, Junqing Huang, Yaqin Chai, Ying Zhuo, Hang Li, and Ruo Yuan*, Programming a “Crab Claw”‑like DNA Nanomachine as a Super Signal Amplifier for Ultrasensitive Electrochemical Assay of Hg2+, Anal. Chem., 2021, 93, 12075-12080.
3)Yuanyuan Chang, Zhongyu Wu, Qianxin Sun, Ying Zhuo, Yaqin Chai*, Ruo Yuan*, Simply Constructed and Highly Efficient Classified Cargo-discharge DNA Robot: A Novel DNA Walking Nanomachine Platform for Ultrasensitive Multiplexed Sensing, Anal. Chem., 2019, 91, 8123-8128.
4)Yuanyuan Chang, Mengyao Li, Zhongyu Wu, Ying Zhuo, Yaqin Chai, Qi Xiao*, and Ruo Yuan*, Homogeneous Entropy Catalytic-Driven DNA Hydrogel as Strong Signal Blocker for Highly Sensitive Electrochemical Detection of Platelet-Derived Growth Factor, Anal. Chem., 2018, 90, 8241-8247.
5)Yuanyuan Chang, Ying Zhuo, Yaqin Chai*, and Ruo Yuan*, Host-Guest Recognition-Assisted Electrochemical Release: Its Reusable Sensing Application Based on DNA Cross Configuration-Fueled Target Cycling and Strand Displacement Reaction Amplification, Anal. Chem., 2017, 89, 8266-8272.
6)Yuanyuan Chang, Ying Zhuo, Yaqin Chai*, Shunbi Xie, and Ruo Yuan*, Novel multifunctionalized peryleneteracarboxylic/amine supramolecules for electrochemical assay, J. Mater. Chem. B, 2016, 4, 5621-5627.
7)Yuanyuan Chang, Shunbi Xie, Yaqin Chai*, Yali Yuan, and Ruo Yuan*,
3,4,9,10-Perylenetetracarboxylic acid/o-phenylenediamine nanomaterials as novel redox probes for electrochemical aptasensor systems based on an Fe3O4 magnetic bead as a nonenzymatic catalyst, Chem. Commun., 2015, 51, 7657-7660.
8)Yuanyuan Chang, Yaqin Chai*, Shunbi Xie, Yali Yuan, Juan Zhang, and Ruo Yuan*, Cleavage-based hybridization chain reaction for electrochemical detection of thrombin, Analyst, 2014, 139, 4264-4269.
科研项目:
1. 国家自然科学基金青年项目(22304125),2024.01-2026.12,30万,主持
2. 中国博士后科学基金第13批特别资助(站中,2020T130544),2020.07-2021.09,18万,主持
3. 重庆市自然科学基金博士后科学基金(cstc2020jcyj-bsh0026),2020.08-2021.09,10万,主持
4. 第66批中国博士后科学基金面上资助(2019M663417),2019.11-2021.09,8万,主持